🔸WHO clinical staging of HIV disease in adults and adolescents🔸
STAGE 1
🔹Asymptomatic
🔹Persistent generalized lymphadenopathy
STAGE 2
🔹Moderate unexplained weight loss (under 10% of presumed or measured body weight)
🔹Recurent respiratory tract infections (sinusitis, tonsillitis, otitis media, pharyngitis)
🔹Herpes zostser
🔹Angular cheilitis
🔹Recurrent oral ulcerations
🔹Papular pruritic eruptions
🔹Seborrhoeic dermatitis
🔹Fungal nail infections
STAGE 3
🔹Unexplained severe weight loss (over 10% of presumed or
measured body weight)
🔹Unexplained chronic diarrhoea for longer than 1 month.
🔹Unexplained persistent fever (intermittent or constant for
longer than 1 month)
🔹Persistent oral candidiasis
🔹Oral hairy leukoplakia
🔹Pulmonary tuberculosis
🔹Severe bacterial infections (e.g. pneumonia, empyema.
meningitis, pyomyositis. bone or joint infection.
bacteraemia, severe pelvic inflammatory disease)
🔹Acute necrotizing ulcerative stomatitis, gingivitis or
periodontitis
🔹Unexplained anaemia (below 8 g/dl), neutropenia
and/or chronic thrombocytopenia
STAGE 4
🔹HIV wasting syndrome
🔹Pneumocystis jiroveci pneumonia
🔹Recurrent severe bacterial pneumonia
🔹Chronic herpes simplex infection
🔹Oesophageal candidiasis (or candidiasis of trachea, bronchi
or lungs)
🔹Extrapulmonary tuberculosis
🔹Kaposi sarcoma
🔹Cytomegalovirus disease
🔹Central nervous system toxoplasmosis
🔹HIV encephalopathy
🔹Extrapulmonary cryptococcosis including meningitis
🔹Disseminated non-tuberculous mycobacteria infection
🔹Progressive multifocal leukoencephalopathy
🔹Chronic cryptosporidiosis
🔹Chronic isosporiasis
🔹Disseminated mycosis (histoplasmosis, coccidiomycosis)
🔹Recurrent septicaemia (including nontyphoidal Salmonella)
🔹Lymphoma (cerebral or B cell non-Hodgkin)
🔹Invasive cervical carcinoma
🔹Atypical disseminated leishmaniasis
🔹Symptomatic HIV-associated nephropathy or HIV-associated
cardiomyopathy.
Sexually transmitted pathogens and diseases caused by them
1) Neisseria gonorrhoea - Gonorrhoea, urethritis, cervicitis, epididymitis, salpingitis, PID, neonatal conjunctivitis
2) Treponema pallidum -
Syphilis
3) Haemophilus ducreyi -
Chancroid
4) Chlamydia trachomatis -
LGV, urethritis, cervicitis, proctitis, epididymitis, infant pneumonia, Reiter's syndrome, PID, neonatal conjunctivitis
5) Klebsiella granulomatis -
Donovanosis (granuloma inguinale)
6) Herpes simplex virus -
Genital herpes
7) Hepatitis B virus -
Acute and chronic hepatitis
8) Human papilloma virus - Genital and anal warts
9) HIV - AIDS
10) Molluscum contagiosum - Genital Molluscum contagiosum
11) Candida albicans - Vaginitis
12) Trichomonas vaginalis - Vaginitis
